All current chapters are members in good standing of the Association for Interdisciplinary Studies and Alpha Iota Sigma. 
Current Alpha Iota Sigma Chapters (2024/25):

Athens State University

Colorado State University

Creighton University

Elizabeth City State University

Mercer University

Morgan State University

North Carolina Agricultural and Technical State University

North Greenville University

Northern Kentucky University

Oakland University

Plymouth State University

Southern Utah University

Spalding University

University of North Carolina – Charlotte

University of West Georgia